John M Graham Selected Research

Teratogens

11/2005	Marshall J. Edwards: discoverer of maternal hyperthermia as a human teratogen.
12/2003	Syndromic immunodeficiencies: genetic syndromes associated with immune abnormalities.

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John M Graham Research Topics

Disease

7	Intellectual Disability (Idiocy) 07/2022 - 11/2013
5	Microcephaly 01/2021 - 06/2011
4	Megalencephaly 01/2021 - 06/2012
4	Seizures (Absence Seizure) 01/2018 - 05/2012
3	Muscle Hypotonia (Hypotonia) 01/2020 - 05/2012
3	Opitz-Kaveggia syndrome 11/2013 - 11/2003
2	Polymicrogyria 01/2021 - 01/2004
2	Neurodevelopmental Disorders 01/2020 - 12/2019
2	Brain Diseases (Brain Disorder) 09/2018 - 10/2016
2	Ataxia (Dyssynergia) 01/2018 - 01/2004
2	Periventricular Nodular Heterotopia 12/2015 - 05/2013
2	Clubfoot (Talipes Equinovarus) 04/2014 - 03/2003
2	Nonsynostotic Plagiocephaly 02/2014 - 02/2005
2	Craniosynostoses (Craniosynostosis) 02/2010 - 02/2005
1	Hydrocephalus (Hydrocephaly) 01/2021
1	Polydactyly (Polydactylism) 01/2021
1	Congenital anosmia 01/2020
1	Apraxias (Dyspraxia) 01/2020
1	Heart Arrest (Cardiac Arrest) 01/2019
1	Hypoparathyroidism- retardation- dysmorphism syndrome 01/2018
1	Quadriplegia (Spastic Quadriplegia) 10/2016
1	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2016
1	Optic Atrophy 10/2016
1	Atrophy 10/2016
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2016
1	Stillbirth 01/2016
1	Congenital Abnormalities (Deformity) 04/2014
1	Scoliosis 04/2014
1	Lujan Fryns syndrome 11/2013
1	Bohring syndrome 01/2013
1	Hypoglycemia (Reactive Hypoglycemia) 05/2012
1	Glut1 Deficiency Syndrome 05/2012
1	Movement Disorders (Movement Disorder) 05/2012
1	Acrodysostosis 04/2012
1	Type II Microcephalic Osteodysplastic Primordial Dwarfism 06/2011
1	Pontocerebellar Hypoplasia Type 1 01/2011
1	Pontocerebellar Hypoplasia Type 6 01/2011
1	Pontocerebellar Hypoplasia 01/2011
1	Hypophosphatasia 01/2010
1	Cleidocranial Dysplasia (Cleidocranial Dysostosis) 01/2010
1	Metabolic Bone Diseases (Osteopenia) 01/2010
1	Gestational Diabetes (Gestational Diabetes Mellitus) 01/2009
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2009
1	Type 2 Diabetes Mellitus (MODY) 01/2009
1	Auditory neuropathy 03/2008
1	CHARGE Syndrome 02/2006
1	Hyperthermia 11/2005
1	Greig cephalopolysyndactyly syndrome 04/2005
1	Pallister-Hall Syndrome 04/2005
1	Choanal Atresia 03/2005
1	Congenital Hip Dislocation 03/2005
1	Hypogonadism (Hypergonadotropic Hypogonadism) 03/2005
1	Warburg Sjo Fledelius syndrome 03/2005
1	Borjeson-Forssman-Lehmann syndrome 12/2004
1	Larsen Syndrome 04/2004

Drug/Important Bio-Agent (IBA)

6	Proteins (Proteins, Gene)FDA Link 07/2022 - 11/2013
3	Transcription Factors (Transcription Factor)IBA 01/2010 - 12/2004
2	Mi-2 Nucleosome Remodeling and Deacetylase ComplexIBA 01/2020 - 12/2019
2	EnzymesIBA 01/2020 - 06/2012
2	Nonsense Codon (Nonsense Mutation)IBA 01/2018 - 01/2013
2	TubulinIBA 01/2018 - 10/2016
2	Lactic Acid (Lactate)FDA LinkGeneric 05/2012 - 01/2011
2	Hormones (Hormone)IBA 04/2012 - 03/2005
2	TeratogensIBA 11/2005 - 12/2003
1	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2020
1	Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA 09/2018
1	Phenylalanine (L-Phenylalanine)FDA Link 09/2018
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 06/2017
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 10/2016
1	Inosine Triphosphate (ITP)IBA 01/2016
1	Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA 12/2015
1	FilaminsIBA 05/2013
1	Deubiquitinating EnzymesIBA 05/2013
1	Glucose (Dextrose)FDA LinkGeneric 05/2012
1	Monoamine Oxidase (MAO)IBA 05/2012
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 04/2012
1	Centrosomal Associated ProteinsIBA 06/2011
1	splicing endonucleaseIBA 01/2011
1	Ligases (Synthetase)IBA 01/2011
1	Transfer RNA (tRNA)IBA 01/2011
1	Alkaline PhosphataseIBA 01/2010
1	N- (4'- fluorobutyrophenone)- 4- (4- chlorophenyl)pyridinium (HPP(+))IBA 01/2010
1	Insulin (Novolin)FDA Link 01/2009
1	N-acetyltalosaminuronic acid (NAT)IBA 12/2008
1	Carrier Proteins (Binding Protein)IBA 02/2006
1	DNA HelicasesIBA 02/2006
1	Retinaldehyde (Retinal)IBA 03/2005
1	Neurotransmitter Agents (Neurotransmitter)IBA 03/2005
1	GTPase-Activating Proteins (GTPase-Activating Protein)IBA 03/2005
1	Codon (Codons)IBA 04/2004

Therapy/Procedure

3	Therapeutics 01/2009 - 02/2005
1	Resuscitation 01/2019
1	Transjugular Intrahepatic Portasystemic Shunt 04/2014
1	Orthotic Devices (Orthosis) 02/2014
1	Precision Medicine 05/2012
1	Ketogenic Diet 05/2012
1	Sutures (Suture) 02/2010
1	Glycemic Control 01/2009
1	Cochlear Implantation 03/2008
1	Induced Hyperthermia (Thermotherapy) 11/2005